A regenerative skin treatment at our Weybridge clinic that helps repair, hydrate and strengthen tired, thin or crepey skin, including the delicate under-eye area.
Polynucleotides are purified DNA fragments that support your skin's own repair processes. Rather than adding volume like a filler, they encourage healthier, more resilient skin from within, improving hydration, elasticity and texture while keeping your natural features unchanged.
At a glance
Appointment about 45 minutes, including numbing
Downtime minimal, small bumps settle within 24 to 48 hours
Results build gradually from about 4 weeks
How long it lasts around 6 to 12 months after a course
Price £300 per session, or a course of 3 for £800 (see price list)
What can it treat?
Dark circles and crepey skin under the eyes
Fine lines and wrinkles
Loss of firmness and elasticity
Dull, dehydrated or tired-looking skin
Uneven skin texture and acne scarring
Redness and sensitive, reactive skin
Sun damage
Crepey skin on the neck and décolletage
Your consultation
Every treatment at our Weybridge clinic starts with a consultation. We take a full medical history, look closely at your skin, and talk honestly about what you would like to achieve, so we only recommend treatment that is safe and right for you. All treatments are carried out by our advanced nurse practitioner and independent prescriber.
The treatment
We treat the under-eye area, full face, and neck and décolletage at our clinic in Weybridge, Surrey. After applying numbing cream, polynucleotides are placed just beneath the skin with a fine needle or cannula. We recommend a course of 3 sessions, 2 to 3 weeks apart, followed by a maintenance session every 6 to 12 months. Polynucleotides can also be combined with anti-wrinkle injections, skin boosters and skin treatments such as microneedling.
Aftercare
Small bumps at the injection points are normal and settle within 24 to 48 hours, and you may have some redness or minor bruising. For 24 hours, avoid make-up, strenuous exercise and alcohol, and for a few days avoid saunas, steam rooms and strong sun. Read our full aftercare advice.
Your results
Results build gradually as your skin repairs itself. Many clients notice brighter, more hydrated skin from about 4 weeks, with the best results 2 to 3 months after completing the course. Depending on the individual, they last around 6 to 12 months.
Is it right for me?
Polynucleotides suit most skin types and ages. They are not suitable if you are pregnant or breastfeeding, have a fish or salmon allergy, or have an active skin infection in the treatment area. We will check your suitability at your consultation.
Related treatments
Profhilo · Jalupro · Sunekos · Skin Boosters · Exosomes




